Everything depends on what you want to end up with.
For example: using the same computer, opti-spark, OEM harness, OBD1/2, etc., or, , ,
Old school simplicity;
Stand alone distributor (HEI), 4bbl carb, 4 into 1 headers, std water pump, one wire alternator, etc., and ALL very easy to do, when converting in that direction, or, , ,
Reverse cool heads and a specially modified block (if 010) is doable, although a TON of work and money, thus not what you would want to do here.
Knock sensors with 1/4" pipe threads actually would screw directly into the two side coolant drain holes centered above the oil pan rails on the 010 block.
And two piece rear main seals are very good, and you have to really miss something obvious to have a newly installed 2-Piece rear main seal leak!
I see combining an "010" block with a 383 crank (3.750"), L31 heads, simple 4bbl carb, HEI, retro-hyd-roller cam as being VERY SIMPLE, RELIABLE, AFFORDABLE, and FAST!
You will need a conversion flywheel as well, but items such as these are small potatoes, and usually need to be bought new anyway, due to age and use/abuse issues.